Enzymatic Relief for Hide & Hoof Conditions

Manage and prevent conditions of the hoof and hide with performance ready solutions for your pleasure or competition horse. ZYMOX Equine Defense enzymatic products utilizes the power of enzymes to nurture, soothe and support skin and hooves of horses as well as care for livestock. Antibiotic- and steroid-free, these proven products are easy-to-use and contain beneficial ingredients to promote healthy skin and hooves .

Available at

Plus at veterinary clinics and other retailers

Skin Defense for Your Horse

  • Promote healthy skin and coat
  • No sting application
  • No astringents, alcohol, chlorines or detergents
  • No antibiotics
  • No steroids
  • Water-based
  • Non-toxic
  • Test clean

Which Equine Product Should be Used?


What is the difference between the new shampoo and conditioner and the previous skin wash and skin guard?

The ZYMOX Equine Defense line introduced the Advanced Formula Shampoo and Advanced Formula Leave-On Conditioner, replacing the Skin Wash and Skin Guard. The patented LP3 Enzyme System remains the same, as do the directions but the main difference is the oat extract. These products are still great for promoting healthy skin but the addition of oat extract helps to make these products extra beneficial to horses and livestock with very dry, irritated skin.

What is the Avena Sativa in the equine defense advanced formula shampoo and leave-on conditioner?

Avena Sativa extract is derived from oat, also known as oat extract, and used in many skin and hair products. It is beneficial in helping to aid in healing itchy, raw, dry skin.


How do I ensure optimal results when used for irritated skin?

In order to optimize results using ZYMOX Equine Defense Topical Spray or Cream, follow the no pre-cleaning protocol. Rinsing the area with water is allowed, however, no cleaning or antiseptic agent is necessary before using ZYMOX topicals. When dealing with itchy allergy skin and general superficial skin irritations, many horse owners have found ZYMOX Equine Defense Skin & Coat Wash and Skin Guard to be excellent additions to the Cream and Spray.

Does ZYMOX Equine Defense contain steroids?

No steroids are used, only natural enzymes so your horse will test clean.

How is ZYMOX Equine Defense products different from other products on the market?

The ZYMOX Equine Defense products contains no antibiotics or harsh chemicals but rather employs the powerful & patented LP3 enzyme system. The products can safely be used on horses of all ages.

Which ZYMOX Equine Defense product is best for application to the hoof and frog?

Because of its viscosity, the ZYMOX Equine Defense Cream provides a perfect vehicle to carry the active enzyme ingredients and allows for quick adherence to the hoof, frog and other areas of the horse. The tube features a catheter tip for easy, targeted application.

Proudly Made in the USA

Pet King Brands is committed to providing quality products proudly made in the USA that are safe, effective and free of harmful ingredients so animals can lead healthy, happy lives.

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